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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 14.24
Human Site: S411 Identified Species: 22.38
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S411 R L P P E E A S P Y V V D H G
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S411 R L P P E E A S P Y V V D H G
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 E366 D R N N R G T E P F V T G V R
Dog Lupus familis XP_850963 1096 118584 S413 R L P P E E A S P Y V V D H G
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L414 L L H P F K D L V Q L P V V T
Rat Rattus norvegicus NP_001102926 1095 118506 S412 R L P P E E A S P Y V V D H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 P397 C S C V N E V P Q F Y F Q H L
Chicken Gallus gallus XP_421617 1147 124543 L464 T L P P E E T L P Y L V D H G
Frog Xenopus laevis NP_001087832 1126 123503 P443 T L P G D E L P P C I V D H V
Zebra Danio Brachydanio rerio XP_700597 1315 142554 P610 T L P P D E S P P Y L V D H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 E592 R I A E G E Y E P P I V D M G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 R467 E T I N N E N R P P I V D H G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 P416 L S H P S E E P I Q V V D F G
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 D244 S V Y V F L L D V S Q N A V K
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 S318 W D A A A Q K S V D R W Q R P
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 13.3 100 N.A. 13.3 100 N.A. 13.3 73.3 46.6 66.6 N.A. N.A. 40 N.A. 40
P-Site Similarity: 100 100 20 100 N.A. 26.6 100 N.A. 20 80 60 86.6 N.A. N.A. 53.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 40 0 6.6
P-Site Similarity: N.A. N.A. N.A. 40 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 7 7 0 27 0 0 0 0 0 7 0 0 % A
% Cys: 7 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 7 0 0 14 0 7 7 0 7 0 0 67 0 0 % D
% Glu: 7 0 0 7 34 74 7 14 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 14 0 0 0 0 14 0 7 0 7 0 % F
% Gly: 0 0 0 7 7 7 0 0 0 0 0 0 7 0 60 % G
% His: 0 0 14 0 0 0 0 0 0 0 0 0 0 60 0 % H
% Ile: 0 7 7 0 0 0 0 0 7 0 20 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 7 % K
% Leu: 14 54 0 0 0 7 14 14 0 0 20 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 7 14 14 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 47 54 0 0 0 27 67 14 0 7 0 0 7 % P
% Gln: 0 0 0 0 0 7 0 0 7 14 7 0 14 0 0 % Q
% Arg: 34 7 0 0 7 0 0 7 0 0 7 0 0 7 7 % R
% Ser: 7 14 0 0 7 0 7 34 0 7 0 0 0 0 0 % S
% Thr: 20 7 0 0 0 0 14 0 0 0 0 7 0 0 7 % T
% Val: 0 7 0 14 0 0 7 0 20 0 40 67 7 20 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 0 0 40 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _